Notre bilan

Années de recherche
Publications internationales

Nos domaines d'expertise

Culture des fibroplastes

Culture medium for gingival fibroplasts


Device for administration cells and cell-therapy method using said device


Use of gingival fibroplasts for vascular cell-therapy

Dermato Cosmétique

Method for the cosmetic treatment of skin photo-aging

Dermato Cosmétique

Compositions useful for the treatment of immune-related disease


Pharmaceutical composition for the treatment of orthopedic pathologies


Method for treating cancer


Use of gingival fibroplasts for the treatment of alopecia

Orthopédie vétérinaire

Composition pour le traitement d’une affection de l’appareil locomoteur

Dermato Thérapeutique

Method for treating skin wounds

Nos publications

Preservation of rabbit aorta elastin from degradation by gingival fibroblasts in an ex vivo model.

Gogly B, Naveau A, Fournier B, Reinald N, Durand E, Brasselet C, Coulomb B, Lafont A. Arterioscler Thromb Vasc Biol. 2007 Sep;27(9):1984-90.

Gingival fibroblasts inhibit MMP-1 and MMP-3 activities in an ex-vivo artery model.

Naveau A, Reinald N, Fournier B, Durand E, Lafont A, Coulomb B, Gogly B. Connect Tissue Res. 2007;48(6):300-8

Gingival fibroblast inhibits MMP-7: evaluation in an ex vivo aorta model.

Gogly B, Fournier B, Couty L, Naveau A, Brasselet C, Durand E, Coulomb B, Lafont A. J Mol Cell Cardiol. 2009 Aug;47(2):296-303.

Fusiform aneurysm model in rabbit carotid artery.

Reinald N, Fournier B, Naveau A, Couty L, Lemitre M, Seguier S, Coulomb B, Gogly B, Lafont A, Durand E. J Vasc Res. 2010;47(1):61-8.

Multipotent progenitor cells in gingival connective tissue.

Fournier BP, Ferre FC, Couty L, Lataillade JJ, Gourven M, Naveau A, Coulomb B, Lafont A, Gogly B. Tissue Eng Part A. 2010 Sep;16(9):2891-9.

Phenotypic study of human gingival fibroblasts in a medium enriched with plateletlysate.

Naveau A, Lataillade JJ, Fournier BP, Couty L, Prat M, Ferre FC, Gourven M, Durand E, Coulomb B, Lafont A, Gogly B. J Periodontol. 2011 Apr;82(4):632-41.

Endoluminal gingival fibroblast transfer reduces the size of rabbit carotid aneurisms via elastin repair.

Durand E, Fournier B, Couty L, Lemitre M, Achouh P, Julia P, Trinquart L, Fabiani JN, Seguier S, Gogly B, Coulomb B, Lafont A. Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):1892-901.

Inhibition of the differentiation of monocyte-derived dendritic cells by human gingival fibroblasts.

Séguier S, Tartour E, Guérin C, Couty L, Lemitre M, Lallement L, Folliguet M, El Naderi S, Terme M, Badoual C, Lafont A, Coulomb B. PLoS One. 2013 Aug 2;8(8):e70937.

Therapeutic potential of gingival fibroblasts for cutaneous radiation syndrome: Comparison to bone marrow-MSC grafts.

Linard C, Tissedre F, Busson E, Holler V, Leclerc T, Strup-Perrot C, Couty L, Lhomme B, Benderitter M, Lafont A, Lattaillade JJ, Coulomb B. Stem Cells Dev 2015 May 15;24(10):1182-93.

Gingival Fibroblasts Protect Against Experimental Abdominal Aortic Aneurysm Development and Rupture Through Tissue Inhibitor of Metalloproteinase-1 Production.

Andreas Giraud, Lynda Zeboudj, Marie Vandestienne, Jérémie Joffre, Bruno Esposito, Stéphane Potteaux , José Vilar, Daniela Cabuzu, Johannes Kluwe, Sylvie Seguier, Alain Tedgui, Ziad Mallat, Antoine Lafont , Hafid Ait-Oufella. Cardiovasc Res 113 (11), 1364-1375. 2017 Sep 01.

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